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Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle
BACKGROUND: Defects in skeletal muscle fatty acid oxidation have been implicated in the etiology of insulin resistance. Malonyl-CoA decarboxylase (MCD) has been a target of investigation because it reduces the concentration of malonyl-CoA, a metabolite that inhibits fatty acid oxidation. The in vivo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236586/ https://www.ncbi.nlm.nih.gov/pubmed/25152047 http://dx.doi.org/10.1186/1471-2091-15-20 |