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Chemical-genetic induction of Malonyl-CoA decarboxylase in skeletal muscle

BACKGROUND: Defects in skeletal muscle fatty acid oxidation have been implicated in the etiology of insulin resistance. Malonyl-CoA decarboxylase (MCD) has been a target of investigation because it reduces the concentration of malonyl-CoA, a metabolite that inhibits fatty acid oxidation. The in vivo...

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Detalles Bibliográficos
Autores principales:	Rodriguez, Susana, Ellis, Jessica M, Wolfgang, Michael J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236586/ https://www.ncbi.nlm.nih.gov/pubmed/25152047 http://dx.doi.org/10.1186/1471-2091-15-20

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