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Common Variations in BMP4 Confer Genetic Susceptibility to Sporadic Congenital Heart Disease in a Han Chinese Population

Congenital heart disease (CHD) is the most common birth defect in humans. The genetic causes of sporadic CHD remain largely unknown. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor-β (TGF-β) family, is required for normal heart development. Loss of BMP4 gene expressio...

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Detalles Bibliográficos
Autores principales: Qian, Bo, Mo, Ran, Da, Min, Peng, Wei, Hu, Yuanli, Mo, Xuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236636/
https://www.ncbi.nlm.nih.gov/pubmed/25022354
http://dx.doi.org/10.1007/s00246-014-0951-1