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Common Variations in BMP4 Confer Genetic Susceptibility to Sporadic Congenital Heart Disease in a Han Chinese Population
Congenital heart disease (CHD) is the most common birth defect in humans. The genetic causes of sporadic CHD remain largely unknown. Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor-β (TGF-β) family, is required for normal heart development. Loss of BMP4 gene expressio...
Autores principales: | Qian, Bo, Mo, Ran, Da, Min, Peng, Wei, Hu, Yuanli, Mo, Xuming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236636/ https://www.ncbi.nlm.nih.gov/pubmed/25022354 http://dx.doi.org/10.1007/s00246-014-0951-1 |
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