Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells

Human SEMAPHORIN 5A (SEMA5A) is an autism susceptibility gene; however, its function in brain development is unknown. In this study, we show that mouse Sema5A negatively regulates synaptogenesis in early, developmentally born, hippocampal dentate granule cells (GCs). Sema5A is strongly expressed by...

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Detalles Bibliográficos
Autores principales: Duan, Yuntao, Wang, Shih-Hsiu, Song, Juan, Mironova, Yevgeniya, Ming, Guo-li, Kolodkin, Alex L, Giger, Roman J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236683/
https://www.ncbi.nlm.nih.gov/pubmed/25313870
http://dx.doi.org/10.7554/eLife.04390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236683/
https://www.ncbi.nlm.nih.gov/pubmed/25313870
http://dx.doi.org/10.7554/eLife.04390

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