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Structural insight into the recognition of amino-acylated initiator tRNA by eIF5B in the 80S initiation complex

BACKGROUND: From bacteria to eukarya, the specific recognition of the amino-acylated initiator tRNA by the universally conserved translational GTPase eIF5B/IF2 is one of the most central interactions in the process of translation initiation. However, the molecular details, particularly also in the c...

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Detalles Bibliográficos
Autores principales: Kuhle, Bernhard, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236685/
https://www.ncbi.nlm.nih.gov/pubmed/25350701
http://dx.doi.org/10.1186/s12900-014-0020-2