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Structural insight into the recognition of amino-acylated initiator tRNA by eIF5B in the 80S initiation complex
BACKGROUND: From bacteria to eukarya, the specific recognition of the amino-acylated initiator tRNA by the universally conserved translational GTPase eIF5B/IF2 is one of the most central interactions in the process of translation initiation. However, the molecular details, particularly also in the c...
Autores principales: | Kuhle, Bernhard, Ficner, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236685/ https://www.ncbi.nlm.nih.gov/pubmed/25350701 http://dx.doi.org/10.1186/s12900-014-0020-2 |
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