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Finding trans-regulatory genes and protein complexes modulating meiotic recombination hotspots of human, mouse and yeast
BACKGROUND: The regulatory mechanism of recombination is one of the most fundamental problems in genomics, with wide applications in genome wide association studies (GWAS), birth-defect diseases, molecular evolution, cancer research, etc. Recombination events cluster into short genomic regions calle...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236725/ https://www.ncbi.nlm.nih.gov/pubmed/25208583 http://dx.doi.org/10.1186/s12918-014-0107-1 |