Cargando…

Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65

Glycyrrhizic acid (GA) is a natural product with favorable antitumor activity. But, glycyrrhetinic acid monoglucuronide (GAMG) showed stronger antitumor activity than GA. It is of our interest to generate and identify novel compounds with regulation telomerase for cancer therapy. So, in this study,...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Wen-jian, Yang, Yong-an, Xu, He, Shi, Jing-bo, Liu, Xin-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236752/
https://www.ncbi.nlm.nih.gov/pubmed/25407586
http://dx.doi.org/10.1038/srep07106