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Synthesis and discovery of 18α-GAMG as anticancer agent in vitro and in vivo via down expression of protein p65
Glycyrrhizic acid (GA) is a natural product with favorable antitumor activity. But, glycyrrhetinic acid monoglucuronide (GAMG) showed stronger antitumor activity than GA. It is of our interest to generate and identify novel compounds with regulation telomerase for cancer therapy. So, in this study,...
Autores principales: | Tang, Wen-jian, Yang, Yong-an, Xu, He, Shi, Jing-bo, Liu, Xin-hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236752/ https://www.ncbi.nlm.nih.gov/pubmed/25407586 http://dx.doi.org/10.1038/srep07106 |
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