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A depth-first search algorithm to compute elementary flux modes by linear programming

BACKGROUND: The decomposition of complex metabolic networks into elementary flux modes (EFMs) provides a useful framework for exploring reaction interactions systematically. Generating a complete set of EFMs for large-scale models, however, is near impossible. Even for moderately-sized models (<4...

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Detalles Bibliográficos
Autores principales: Quek, Lake-Ee, Nielsen, Lars K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236763/
https://www.ncbi.nlm.nih.gov/pubmed/25074068
http://dx.doi.org/10.1186/s12918-014-0094-2