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A depth-first search algorithm to compute elementary flux modes by linear programming
BACKGROUND: The decomposition of complex metabolic networks into elementary flux modes (EFMs) provides a useful framework for exploring reaction interactions systematically. Generating a complete set of EFMs for large-scale models, however, is near impossible. Even for moderately-sized models (<4...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236763/ https://www.ncbi.nlm.nih.gov/pubmed/25074068 http://dx.doi.org/10.1186/s12918-014-0094-2 |