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Photo-sensitive degron variants for tuning protein stability by light

BACKGROUND: Regulated proteolysis by the proteasome is one of the fundamental mechanisms used in eukaryotic cells to control cellular behavior. Efficient tools to regulate protein stability offer synthetic influence on molecular level on a selected biological process. Optogenetic control of protein...

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Detalles Bibliográficos
Autores principales: Usherenko, Svetlana, Stibbe, Hilke, Muscò, Massimiliano, Essen, Lars-Oliver, Kostina, Ekaterina A, Taxis, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236813/
https://www.ncbi.nlm.nih.gov/pubmed/25403319
http://dx.doi.org/10.1186/s12918-014-0128-9