An In Vitro Analysis of the Effects of Intravenous Lipid Emulsion on Free and Total Local Anaesthetic Concentrations in Human Blood and Plasma

Background. Intravenous lipid emulsion (ILE) is recommended as a “rescue” treatment for local anaesthetic (LA) toxicity. A purported mechanism of action suggests that lipophilic LAs are sequestered into an intravascular “lipid-sink,” thus reducing free drug concentration. There is limited data avail...

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Detalles Bibliográficos
Autores principales: Clark, Louise Ann, Beyer, Jochen, Graudins, Andis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236888/
https://www.ncbi.nlm.nih.gov/pubmed/25538850
http://dx.doi.org/10.1155/2014/236520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236888/
https://www.ncbi.nlm.nih.gov/pubmed/25538850
http://dx.doi.org/10.1155/2014/236520

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