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Disruption of the LTD dialogue between the cerebellum and the cortex in Angelman syndrome model: a timing hypothesis

Angelman syndrome (AS) is a genetic neurodevelopmental disorder in which cerebellar functioning impairment has been documented despite the absence of gross structural abnormalities. Characteristically, a spontaneous 160 Hz oscillation emerges in the Purkinje cells network of the Ube3a(m−/p+) Angelma...

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Detalles Bibliográficos
Autores principales: Cheron, Guy, Márquez-Ruiz, Javier, Kishino, Tatsuya, Dan, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237040/
https://www.ncbi.nlm.nih.gov/pubmed/25477791
http://dx.doi.org/10.3389/fnsys.2014.00221