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Infected hematopoietic stem cells and with integrated HBV DNA generate defective T cells in chronic HBV infection patients

A weak T-cell response plays a key role in the persistence of hepatitis B virus (HBV) infection. We aimed to confirm that T-cell defects in patients with chronic HBV infection are associated with HBV DNA infection of bone marrow (BM) hematopoietic stem cells (HSCs). Using reverse transcription polym...

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Detalles Bibliográficos
Autores principales: Shi, Y, Lan, Y, Cao, F, Teng, Y, Li, L, Wang, F, Li, J, Zhou, J, Li, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237112/
https://www.ncbi.nlm.nih.gov/pubmed/24620791
http://dx.doi.org/10.1111/jvh.12236