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Infected hematopoietic stem cells and with integrated HBV DNA generate defective T cells in chronic HBV infection patients
A weak T-cell response plays a key role in the persistence of hepatitis B virus (HBV) infection. We aimed to confirm that T-cell defects in patients with chronic HBV infection are associated with HBV DNA infection of bone marrow (BM) hematopoietic stem cells (HSCs). Using reverse transcription polym...
Autores principales: | Shi, Y, Lan, Y, Cao, F, Teng, Y, Li, L, Wang, F, Li, J, Zhou, J, Li, Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237112/ https://www.ncbi.nlm.nih.gov/pubmed/24620791 http://dx.doi.org/10.1111/jvh.12236 |
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