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Randomized, double-blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy

Glycerol phenylbutyrate (GPB) lowers ammonia by providing an alternate pathway to urea for waste nitrogen excretion in the form of phenylacetyl glutamine, which is excreted in urine. This randomized, double-blind, placebo-controlled phase II trial enrolled 178 patients with cirrhosis, including 59 a...

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Detalles Bibliográficos
Autores principales: Rockey, Don C, Vierling, John M, Mantry, Parvez, Ghabril, Marwan, Brown, Robert S, Alexeeva, Olga, Zupanets, Igor A, Grinevich, Vladimir, Baranovsky, Andrey, Dudar, Larysa, Fadieienko, Galyna, Kharchenko, Nataliya, Klaryts'ka, Iryna, Morozov, Vyacheslav, Grewal, Priya, McCashland, Timothy, Reddy, K Gautham, Reddy, K Rajender, Syplyviy, Vasyl, Bass, Nathan M, Dickinson, Klara, Norris, Catherine, Coakley, Dion, Mokhtarani, Masoud, Scharschmidt, Bruce F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237123/
https://www.ncbi.nlm.nih.gov/pubmed/23847109
http://dx.doi.org/10.1002/hep.26611