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MOZ-Mediated Repression of p16(INK)(4)(a) Is Critical for the Self-Renewal of Neural and Hematopoietic Stem Cells

Although inhibition of p16(INK4a) expression is critical to preserve the proliferative capacity of stem cells, the molecular mechanisms responsible for silencing p16(INK4a) expression remain poorly characterized. Here, we show that the histone acetyltransferase (HAT) monocytic leukemia zinc finger p...

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Detalles Bibliográficos
Autores principales: Perez-Campo, Flor M, Costa, Guilherme, Lie-a-Ling, Michael, Stifani, Stefano, Kouskoff, Valerie, Lacaud, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237135/
https://www.ncbi.nlm.nih.gov/pubmed/24307508
http://dx.doi.org/10.1002/stem.1606