Corrections for mRNA extraction and sample normalization errors find increased mRNA levels may compensate for cancer haplo-insufficiency

The relative mRNA levels of differentially expressed (DE) and housekeeping (HK) genes of six aneuploid cancer lines with large-scale genomic changes identified by SNP/SKY analysis were compared with similar genes in diploid cells. The aneuploid cancer lines had heterogeneous genomic landscapes with...

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Detalles Bibliográficos
Autores principales: Weaver, David A, Nestor-Kalinoski, Andrea L, Craig, Kristen, Gorris, Matthew, Parikh, Tejal, Mabry, Helen, Allison, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237174/
https://www.ncbi.nlm.nih.gov/pubmed/24327546
http://dx.doi.org/10.1002/gcc.22133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237174/
https://www.ncbi.nlm.nih.gov/pubmed/24327546
http://dx.doi.org/10.1002/gcc.22133

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