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Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser(727)

Chronic lymphoid leukemia (CLL) is characterized by the accumulation of functionally defective CD5-positive B lymphocytes. The clinical course of CLL is highly variable, ranging from a long-lasting indolent disease to an unpredictable and rapidly progressing leukemia requiring treatment. It is thus...

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Detalles Bibliográficos
Autores principales: Capron, C, Jondeau, K, Casetti, L, Jalbert, V, Costa, C, Verhoyen, E, Massé, J M, Coppo, P, Béné, M C, Bourdoncle, P, Cramer-Bordé, E, Dusanter-Fourt, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237234/
https://www.ncbi.nlm.nih.gov/pubmed/25299776
http://dx.doi.org/10.1038/cddis.2014.393