Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca(2+) influx, necrosis and neutrophil extracellular trap formation

Mycobacterium tuberculosis infection generates pulmonary granulomas that consist of a caseous, necrotic core surrounded by an ordered arrangement of macrophages, neutrophils and T cells. This inflammatory pathology is essential for disease transmission and M. tuberculosis has evolved to stimulate in...

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Detalles Bibliográficos
Autores principales: Francis, R J, Butler, R E, Stewart, G R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237235/
https://www.ncbi.nlm.nih.gov/pubmed/25321481
http://dx.doi.org/10.1038/cddis.2014.394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237235/
https://www.ncbi.nlm.nih.gov/pubmed/25321481
http://dx.doi.org/10.1038/cddis.2014.394

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