SMAR1 coordinates HDAC6-induced deacetylation of Ku70 and dictates cell fate upon irradiation

Acetylation status of DNA end joining protein Ku70 dictates its function in DNA repair and Bax-mediated apoptosis. Despite the knowledge of HDACs and HATs that are reported to modulate the acetylation dynamics of Ku70, very little is known about proteins that critically coordinate these key modifica...

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Detalles Bibliográficos
Autores principales: Chaudhary, N, Nakka, K K, Chavali, P L, Bhat, J, Chatterjee, S, Chattopadhyay, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237237/
https://www.ncbi.nlm.nih.gov/pubmed/25299772
http://dx.doi.org/10.1038/cddis.2014.397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237237/
https://www.ncbi.nlm.nih.gov/pubmed/25299772
http://dx.doi.org/10.1038/cddis.2014.397

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