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Analysis of BH3-only proteins upregulated in response to oxygen/glucose deprivation in cortical neurons identifies Bmf but not Noxa as potential mediator of neuronal injury

Stress signaling in response to oxygen/glucose deprivation (OGD) and ischemic injury activates a group of pro-apoptotic genes, the Bcl-2 homology domain 3 (BH3)-only proteins, which are capable of activating the mitochondrial apoptosis pathway. Targeted studies previously identified the BH3-only pro...

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Detalles Bibliográficos
Autores principales: Pfeiffer, S, Anilkumar, U, Chen, G, Ramírez-Peinado, S, Galindo-Moreno, J, Muñoz-Pinedo, C, Prehn, J H M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237251/
https://www.ncbi.nlm.nih.gov/pubmed/25299781
http://dx.doi.org/10.1038/cddis.2014.426