Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis

ADP-ribosylation-like factor 6 interacting protein 5 (Arl6ip5), which belongs to the prenylated rab-acceptor-family, has an important role in exocytic protein trafficking, glutathione metabolism and involves in cancer progression. However, its expression pattern and functional role in bone are unkno...

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Detalles Bibliográficos
Autores principales: Wu, Y, Yang, M, Fan, J, Peng, Y, Deng, L, Ding, Y, Yang, R, Zhou, J, Miao, D, Fu, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237252/
https://www.ncbi.nlm.nih.gov/pubmed/25321471
http://dx.doi.org/10.1038/cddis.2014.427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237252/
https://www.ncbi.nlm.nih.gov/pubmed/25321471
http://dx.doi.org/10.1038/cddis.2014.427

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