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Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis

The metabolic profiles of cancer cells have long been acknowledged to be altered and to provide new therapeutic opportunities. In particular, a wide range of both solid and liquid tumors use aerobic glycolysis to supply energy and support cell growth. This metabolic program leads to high rates of gl...

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Detalles Bibliográficos
Autores principales: Liu, T, Kishton, R J, Macintyre, A N, Gerriets, V A, Xiang, H, Liu, X, Abel, E D, Rizzieri, D, Locasale, J W, Rathmell, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237255/
https://www.ncbi.nlm.nih.gov/pubmed/25321477
http://dx.doi.org/10.1038/cddis.2014.431