Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis

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The metabolic profiles of cancer cells have long been acknowledged to be altered and to provide new therapeutic opportunities. In particular, a wide range of both solid and liquid tumors use aerobic glycolysis to supply energy and support cell growth. This metabolic program leads to high rates of gl...

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Detalles Bibliográficos
Autores principales: Liu, T, Kishton, R J, Macintyre, A N, Gerriets, V A, Xiang, H, Liu, X, Abel, E D, Rizzieri, D, Locasale, J W, Rathmell, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237255/
https://www.ncbi.nlm.nih.gov/pubmed/25321477
http://dx.doi.org/10.1038/cddis.2014.431
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