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HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation

Acute myeloid leukemia (AML) is recognized as a complex disease of hematopoietic stem cell disorders, but its pathogenesis mechanisms, diagnosis, and treatment remain unclear. General histone deacetylase (HDAC) inhibitors have been used in blood cancers including AML, but the lack of gene specificit...

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Detalles Bibliográficos
Autores principales: Huang, Y, Chen, J, Lu, C, Han, J, Wang, G, Song, C, Zhu, S, Wang, C, Li, G, Kang, J, Wang, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237257/
https://www.ncbi.nlm.nih.gov/pubmed/25341045
http://dx.doi.org/10.1038/cddis.2014.433