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HDAC1 and Klf4 interplay critically regulates human myeloid leukemia cell proliferation
Acute myeloid leukemia (AML) is recognized as a complex disease of hematopoietic stem cell disorders, but its pathogenesis mechanisms, diagnosis, and treatment remain unclear. General histone deacetylase (HDAC) inhibitors have been used in blood cancers including AML, but the lack of gene specificit...
Autores principales: | Huang, Y, Chen, J, Lu, C, Han, J, Wang, G, Song, C, Zhu, S, Wang, C, Li, G, Kang, J, Wang, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237257/ https://www.ncbi.nlm.nih.gov/pubmed/25341045 http://dx.doi.org/10.1038/cddis.2014.433 |
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