Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development

Numb asymmetrically segregates at mitosis to control cell fate choices during development. Numb inheritance specifies progenitor over differentiated cell fates, and, paradoxically, also promotes neuronal differentiation, thus indicating that the role of Numb may change during development. Here we re...

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Detalles Bibliográficos
Autores principales: Martin-Blanco, N M, Checquolo, S, Del Gaudio, F, Palermo, R, Franciosa, G, Di Marcotullio, L, Gulino, A, Canelles, M, Screpanti, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237259/
https://www.ncbi.nlm.nih.gov/pubmed/25321479
http://dx.doi.org/10.1038/cddis.2014.438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237259/
https://www.ncbi.nlm.nih.gov/pubmed/25321479
http://dx.doi.org/10.1038/cddis.2014.438

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