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Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development
Numb asymmetrically segregates at mitosis to control cell fate choices during development. Numb inheritance specifies progenitor over differentiated cell fates, and, paradoxically, also promotes neuronal differentiation, thus indicating that the role of Numb may change during development. Here we re...
Autores principales: | Martin-Blanco, N M, Checquolo, S, Del Gaudio, F, Palermo, R, Franciosa, G, Di Marcotullio, L, Gulino, A, Canelles, M, Screpanti, I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237259/ https://www.ncbi.nlm.nih.gov/pubmed/25321479 http://dx.doi.org/10.1038/cddis.2014.438 |
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