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RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer
A hypoxic tumor microenvironment is characteristic of many cancer types, including one of the most lethal, pancreatic cancer. We recently demonstrated that the receptor for advanced glycation end products (RAGE) has an important role in promoting the development of pancreatic cancer and attenuating...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237264/ https://www.ncbi.nlm.nih.gov/pubmed/25341034 http://dx.doi.org/10.1038/cddis.2014.445 |