Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma

Ovarian cancer patients are typically treated with carboplatin and paclitaxel, but suffer a high rate of relapse with recalcitrant disease. This challenge has fostered the development of novel approaches to treatment, including antagonists of the ‘inhibitor of apoptosis proteins' (IAPs), also c...

Descripción completa

Detalles Bibliográficos
Autores principales: McCabe, K E, Bacos, K, Lu, D, Delaney, J R, Axelrod, J, Potter, M D, Vamos, M, Wong, V, Cosford, N D P, Xiang, R, Stupack, D G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237265/
https://www.ncbi.nlm.nih.gov/pubmed/25356865
http://dx.doi.org/10.1038/cddis.2014.448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237265/
https://www.ncbi.nlm.nih.gov/pubmed/25356865
http://dx.doi.org/10.1038/cddis.2014.448

Ejemplares similares