Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31

Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 and suppresses gene expression by catalyzing histone H3 methylation on lysine 27. EZH2 is overexpressed in metastatic prostate cancer and has been shown to promote cell proliferation and metastasis. Here...

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Detalles Bibliográficos
Autores principales: Zhang, Q, Padi, S K R, Tindall, D J, Guo, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237267/
https://www.ncbi.nlm.nih.gov/pubmed/25341040
http://dx.doi.org/10.1038/cddis.2014.454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237267/
https://www.ncbi.nlm.nih.gov/pubmed/25341040
http://dx.doi.org/10.1038/cddis.2014.454

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