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Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31

Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 and suppresses gene expression by catalyzing histone H3 methylation on lysine 27. EZH2 is overexpressed in metastatic prostate cancer and has been shown to promote cell proliferation and metastasis. Here...

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Detalles Bibliográficos
Autores principales:	Zhang, Q, Padi, S K R, Tindall, D J, Guo, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237267/ https://www.ncbi.nlm.nih.gov/pubmed/25341040 http://dx.doi.org/10.1038/cddis.2014.454

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