An eIF4E-interacting peptide induces cell death in cancer cell lines

The eukaryotic initiation factor eIF4E is essential for cap-dependent initiation of translation in eukaryotes. Abnormal regulation of eIF4E has been implicated in oncogenic transformation. We developed an eIF4E-binding peptide derived from Angel1, a partner of eIF4E that we recently identified. We s...

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Detalles Bibliográficos
Autores principales: Masse, M, Glippa, V, Saad, H, Le Bloas, R, Gauffeny, I, Berthou, C, Czjzek, M, Cormier, P, Cosson, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237268/
https://www.ncbi.nlm.nih.gov/pubmed/25356869
http://dx.doi.org/10.1038/cddis.2014.457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237268/
https://www.ncbi.nlm.nih.gov/pubmed/25356869
http://dx.doi.org/10.1038/cddis.2014.457

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