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NLRP3 inflammasome activation by mitochondrial ROS in bronchial epithelial cells is required for allergic inflammation

Abnormality in mitochondria has been suggested to be associated with development of allergic airway disorders. In this study, to evaluate the relationship between mitochondrial reactive oxygen species (ROS) and NLRP3 inflammasome activation in allergic asthma, we used a newly developed mitochondrial...

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Detalles Bibliográficos
Autores principales: Kim, S R, Kim, D I, Kim, S H, Lee, H, Lee, K S, Cho, S H, Lee, Y C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237270/
https://www.ncbi.nlm.nih.gov/pubmed/25356867
http://dx.doi.org/10.1038/cddis.2014.460