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Overexpression of Mcl-1L Splice Variant Is Associated with Poor Prognosis and Chemoresistance in Oral Cancers

BACKGROUND: Altered expression of Mcl-1, an anti-apoptotic member of the Bcl-2 family, has been linked to the progression and outcome of a variety of malignancies. We have previously reported the overexpression of Mcl-1 protein in human oral cancers. The present study aimed to evaluate the clinicopa...

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Detalles Bibliográficos
Autores principales: Palve, Vinayak, Mallick, Sanchita, Ghaisas, Gauri, Kannan, Sadhana, Teni, Tanuja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237324/
https://www.ncbi.nlm.nih.gov/pubmed/25409302
http://dx.doi.org/10.1371/journal.pone.0111927