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Pharmacological Activation of the EDA/EDAR Signaling Pathway Restores Salivary Gland Function following Radiation-Induced Damage

Radiotherapy of head and neck cancers often results in collateral damage to adjacent salivary glands associated with clinically significant hyposalivation and xerostomia. Due to the reduced capacity of salivary glands to regenerate, hyposalivation is treated by substitution with artificial saliva, r...

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Detalles Bibliográficos
Autores principales: Hill, Grace, Headon, Denis, Harris, Zoey I., Huttner, Kenneth, Limesand, Kirsten H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237357/
https://www.ncbi.nlm.nih.gov/pubmed/25409170
http://dx.doi.org/10.1371/journal.pone.0112840