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Pharmacological Activation of the EDA/EDAR Signaling Pathway Restores Salivary Gland Function following Radiation-Induced Damage
Radiotherapy of head and neck cancers often results in collateral damage to adjacent salivary glands associated with clinically significant hyposalivation and xerostomia. Due to the reduced capacity of salivary glands to regenerate, hyposalivation is treated by substitution with artificial saliva, r...
Autores principales: | Hill, Grace, Headon, Denis, Harris, Zoey I., Huttner, Kenneth, Limesand, Kirsten H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237357/ https://www.ncbi.nlm.nih.gov/pubmed/25409170 http://dx.doi.org/10.1371/journal.pone.0112840 |
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