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Genome Editing in Mouse Spermatogonial Stem/Progenitor Cells Using Engineered Nucleases

Editing the genome to create specific sequence modifications is a powerful way to study gene function and promises future applicability to gene therapy. Creation of precise modifications requires homologous recombination, a very rare event in most cell types that can be stimulated by introducing a d...

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Detalles Bibliográficos
Autores principales: Fanslow, Danielle A., Wirt, Stacey E., Barker, Jenny C., Connelly, Jon P., Porteus, Matthew H., Dann, Christina Tenenhaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237364/
https://www.ncbi.nlm.nih.gov/pubmed/25409432
http://dx.doi.org/10.1371/journal.pone.0112652