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Genome Editing in Mouse Spermatogonial Stem/Progenitor Cells Using Engineered Nucleases
Editing the genome to create specific sequence modifications is a powerful way to study gene function and promises future applicability to gene therapy. Creation of precise modifications requires homologous recombination, a very rare event in most cell types that can be stimulated by introducing a d...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237364/ https://www.ncbi.nlm.nih.gov/pubmed/25409432 http://dx.doi.org/10.1371/journal.pone.0112652 |