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Immunohistochemical Characterization of the Chemosensory Pulmonary Neuroepithelial Bodies in the Naked Mole-Rat Reveals a Unique Adaptive Phenotype

The pulmonary neuroepithelial bodies (NEBs) constitute polymodal airway chemosensors for monitoring and signaling ambient gas concentrations (pO(2), pCO(2)/H(+)) via complex innervation to the brain stem controlling breathing. NEBs produce the bioactive amine, serotonin (5-HT), and a variety of pept...

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Detalles Bibliográficos
Autores principales: Pan, Jie, Park, Thomas J., Cutz, Ernest, Yeger, Herman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237365/
https://www.ncbi.nlm.nih.gov/pubmed/25409164
http://dx.doi.org/10.1371/journal.pone.0112623