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Impaired Autophagy Contributes to Adverse Cardiac Remodeling in Acute Myocardial Infarction

OBJECTIVE: Autophagy is activated in ischemic heart diseases, but its dynamics and functional roles remain unclear and controversial. In this study, we investigated the dynamics and role of autophagy and the mechanism(s), if any, during postinfarction cardiac remodeling. METHODS AND RESULTS: Acute m...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoqian, He, Lishan, Chen, Fajiang, He, Xiaoen, Cai, Yi, Zhang, Guiping, Yi, Quan, He, Meixiang, Luo, Jiandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237367/
https://www.ncbi.nlm.nih.gov/pubmed/25409294
http://dx.doi.org/10.1371/journal.pone.0112891