Uromodulin Retention in Thick Ascending Limb of Henle's Loop Affects SCD1 in Neighboring Proximal Tubule: Renal Transcriptome Studies in Mouse Models of Uromodulin-Associated Kidney Disease

Uromodulin-associated kidney disease (UAKD) is a hereditary progressive renal disease which can lead to renal failure and requires renal replacement therapy. UAKD belongs to the endoplasmic reticulum storage diseases due to maturation defect of mutant uromodulin and its retention in the enlarged end...

Descripción completa

Detalles Bibliográficos
Autores principales: Horsch, Marion, Beckers, Johannes, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabě de Angelis, Martin, Rathkolb, Birgit, Wolf, Eckhard, Aigner, Bernhard, Kemter, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237372/
https://www.ncbi.nlm.nih.gov/pubmed/25409434
http://dx.doi.org/10.1371/journal.pone.0113125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237372/
https://www.ncbi.nlm.nih.gov/pubmed/25409434
http://dx.doi.org/10.1371/journal.pone.0113125

Ejemplares similares