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Hepatitis C Virus Nonstructural Protein 5A Inhibits Thapsigargin-Induced Apoptosis

BACKGROUND: We previously reported that the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) down-regulates TLR4 signaling and lipopolysaccharide-induced apoptosis of hepatocytes. There have been several reports regarding the association between HCV infection and endoplasmic reticulum (ER) st...

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Detalles Bibliográficos
Autores principales: Jiang, Xia, Kanda, Tatsuo, Wu, Shuang, Nakamoto, Shingo, Wakita, Takaji, Shirasawa, Hiroshi, Yokosuka, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237446/
https://www.ncbi.nlm.nih.gov/pubmed/25409163
http://dx.doi.org/10.1371/journal.pone.0113499