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Immunohistochemistry of Colorectal Cancer Biomarker Phosphorylation Requires Controlled Tissue Fixation

Phosphorylated signaling molecules are biomarkers of cancer pathophysiology and resistance to therapy, but because phosphoprotein analytes are often labile, poorly controlled clinical laboratory practices could prevent translation of research findings in this area from the bench to the bedside. We t...

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Detalles Bibliográficos
Autores principales: Theiss, Abbey P., Chafin, David, Bauer, Daniel R., Grogan, Thomas M., Baird, Geoffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237459/
https://www.ncbi.nlm.nih.gov/pubmed/25409462
http://dx.doi.org/10.1371/journal.pone.0113608