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Derivation of human differential photoreceptor cells from adult human dermal fibroblasts by defined combinations of CRX, RAX, OTX2 and NEUROD

Redirecting differentiation of somatic cells by over-expression of transcription factors is a promising approach for regenerative medicine, elucidation of pathogenesis and development of new therapies. We have previously defined a transcription factor combination, that is, CRX, RAX and NEUROD, that...

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Detalles Bibliográficos
Autores principales: Seko, Yuko, Azuma, Noriyuki, Ishii, Toshiyuki, Komuta, Yukari, Miyamoto, Kiyoko, Miyagawa, Yoshitaka, Kaneda, Makoto, Umezawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237506/
https://www.ncbi.nlm.nih.gov/pubmed/24456169
http://dx.doi.org/10.1111/gtc.12127