Cargando…

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

Alzheimer’s disease (AD) is a devastating disease characterized by synaptic and neuronal loss in the elderly. Compelling evidence suggests that soluble amyloid-β peptide (Aβ) oligomers induce synaptic loss in AD. Aβ-induced synaptic dysfunction is dependent on overstimulation of N-methyl-D-aspartate...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Shichun, Okamoto, Shu-ichi, Lipton, Stuart A, Xu, Huaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237769/
https://www.ncbi.nlm.nih.gov/pubmed/25394486
http://dx.doi.org/10.1186/1750-1326-9-48