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Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

Alzheimer’s disease (AD) is a devastating disease characterized by synaptic and neuronal loss in the elderly. Compelling evidence suggests that soluble amyloid-β peptide (Aβ) oligomers induce synaptic loss in AD. Aβ-induced synaptic dysfunction is dependent on overstimulation of N-methyl-D-aspartate...

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Detalles Bibliográficos
Autores principales:	Tu, Shichun, Okamoto, Shu-ichi, Lipton, Stuart A, Xu, Huaxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237769/ https://www.ncbi.nlm.nih.gov/pubmed/25394486 http://dx.doi.org/10.1186/1750-1326-9-48

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