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Enterovirus 71-induced autophagy increases viral replication and pathogenesis in a suckling mouse model

BACKGROUND: We previously reported that Enterovirus 71 (EV71) infection activates autophagy, which promotes viral replication both in vitro and in vivo. In the present study we further investigated whether EV71 infection of neuronal SK-N-SH cells induces an autophagic flux. Furthermore, the effects...

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Detalles Bibliográficos
Autores principales: Lee, Ying-Ray, Wang, Po-Shun, Wang, Jen-Ren, Liu, Hsiao-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237791/
https://www.ncbi.nlm.nih.gov/pubmed/25139436
http://dx.doi.org/10.1186/s12929-014-0080-4