NF-κB repressing factor downregulates basal expression and mycobacterium tuberculosis induced IP-10 and IL-8 synthesis via interference with NF-κB in monocytes

BACKGROUND: Our previous study showed NF-κB repressing factor (NKRF) downregulates IP-10 and IL-8 synthesis in the peripheral blood mononuclear cells and alveolar macrophages of TB patients with high bacterial loads. However, the mechanism underlying the repressive effect of NKRF is not fully unders...

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Detalles Bibliográficos
Autores principales: Huang, Kuo-Hsiung, Wang, Chun-Hua, Lin, Chien-Huang, Kuo, Han-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237804/
https://www.ncbi.nlm.nih.gov/pubmed/25135111
http://dx.doi.org/10.1186/s12929-014-0071-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237804/
https://www.ncbi.nlm.nih.gov/pubmed/25135111
http://dx.doi.org/10.1186/s12929-014-0071-5

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